Chi-un Choe
Priv.-Doz. Dr. med.
Chi-un Choe
MBA
  • Oberarzt
  • Facharzt für Neurologie
Arbeitsbereich

Kontakt

Standort

Hauptgebäude O10 , 2. Etage
Sprachen
Deutsch (Muttersprache)
Englisch

Auszeichnungen

Publikationen

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  • 2019
  • 2018
  • 2017
  • 2016
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  • 2003
Vor

Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans
Bollenbach A, Cordts K, Hanff E, Atzler D, Choe C, Schwedhelm E, Tsikas D
ANAL BIOCHEM. 2019;577:59-66.

Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies
Choe C, Lezius S, Cordts K, Gerloff C, Böger R, Schwedhelm E, Grant P
NEUROL SCI. 2019 [Epub ahead of print].

Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHADS-VASc score in three cross-sectional studies
Cordts K, Grzybowski R, Lezius S, Lüneburg N, Atzler D, Neu A, Hornig S, Böger R, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant P, Choe C
J NEUROL SCI. 2019;397:156-161.

Modulation of specific components of sleep disturbances by simultaneous subthalamic and nigral stimulation in Parkinson's disease
Hidding U, Gulberti A, Pflug C, Choe C, Horn A, Prilop L, Braaß H, Fründt O, Buhmann C, Weiss D, Westphal M, Engel A, Gerloff C, Köppen J, Hamel W, Moll C, Pötter-Nerger M
PARKINSONISM RELAT D. 2019;62:141-147.

Mapping stimulation-induced beneficial and adverse effects in the subthalamic area of essential tremor patients
Hidding U, Schaper M, Moll C, Gulberti A, Köppen J, Buhmann C, Gerloff C, Pötter-Nerger M, Hamel W, Choe C
PARKINSONISM RELAT D. 2019;64:150-155.

Thalamic short pulse stimulation diminishes adverse effects in essential tremor patients
Choe C, Hidding U, Schaper M, Gulberti A, Köppen J, Buhmann C, Gerloff C, Moll C, Hamel W, Pötter-Nerger M
NEUROLOGY. 2018;91(8):e704-e713.

Towards unambiguous reporting of complications related to deep brain stimulation surgery: A retrospective single-center analysis and systematic review of the literature
Engel K, Huckhagel T, Gulberti A, Pötter-Nerger M, Vettorazzi E, Hidding U, Choe C, Zittel S, Braaß H, Ludewig P, Schaper M, Krajewski K, Oehlwein C, Mittmann K, Engel A, Gerloff C, Westphal M, Moll C, Buhmann C, Köppen J, Hamel W
PLOS ONE. 2018;13(8):e0198529.

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine
Faller K, Atzler D, McAndrew D, Zervou S, Whittington H, Simon J, Aksentijevic D, Ten Hove M, Choe C, Isbrandt D, Casadei B, Schneider J, Neubauer S, Lygate C
CARDIOVASC RES. 2018;114(3):417-430.

Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure
Reichold M, Klootwijk E, Reinders J, Otto E, Milani M, Broeker C, Laing C, Wiesner J, Devi S, Zhou W, Schmitt R, Tegtmeier I, Sterner C, Doellerer H, Renner K, Oefner P, Dettmer K, Simbuerger J, Witzgall R, Stanescu H, Dumitriu S, Iancu D, Patel V, Mozere M, Tekman M, Jaureguiberry G, Issler N, Kesselheim A, Walsh S, Gale D, Howie A, Martins J, Hall A, Kasgharian M, O'Brien K, Ferreira C, Atwal P, Jain M, Hammers A, Charles-Edwards G, Choe C, Isbrandt D, Cebrian-Serrano A, Davies B, Sandford R, Pugh C, Konecki D, Povey S, Bockenhauer D, Lichter-Konecki U, Gahl W, Unwin R, Warth R, Kleta R
J AM SOC NEPHROL. 2018;29(7):1849-1858.

Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks
Schönhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, Gerloff C, Böger R, Neu A, Schwedhelm E, Choe C
J CLIN NEUROSCI. 2018;50:237-241.

How does it feel to be operated on the brain? Perceived intraoperative stress of movement disorder patients undergoing awake deep brain stimulation surgery
Sieger J, Gulberti A, Köppen J, Pinnschmidt H, Nitzschke R, Schaper M, Braaß H, Buhmann C, Choe C, Hidding U, Zittel S, Engel A, Mehnert A, Gerloff C, Westphal M, Pötter-Nerger M, Hamel W, Moll C
2018. The many faces of Parkinson’s disease – Motor and non ‐ motor symptoms from prodromal to advanced disease stages. .

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism
Stockebrand M, Sasani A, Das D, Hornig S, Hermans-Borgmeyer I, Lake H, Isbrandt D, Lygate C, Heerschap A, Neu A, Choe C
FRONTIERS IN PHYSIOLOGY. 2018;9:773.

First report of clinical outcomes resulting from use of directional deep brain stimulation in Parkinson's disease and essential tremor
Braaß H, Venkatesan , Choe C, Hidding U, Schönwald B, Wargel C, Buhmann C, Gulberti A, Moll C, Köppen J, Gerloff C, Hamel W, Pötter-Nerger M
2017. Mov Disord . suppl. Aufl. .

Adverse events in deep brain stimulation: A retrospective long-term analysis of neurological, psychiatric and other occurrences
Buhmann C, Huckhagel T, Engel K, Gulberti A, Hidding U, Poetter-Nerger M, Goerendt I, Ludewig P, Braass H, Choe C, Krajewski K, Oehlwein C, Mittmann K, Engel A, Gerloff C, Westphal M, Köppen J, Moll C, Hamel W
PLOS ONE. 2017;12(7):e0178984.

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain
Atzler D, Baum C, Ojeda F, Keller T, Cordts K, Schnabel R, Choe C, Lackner K, Münzel T, Böger R, Blankenberg S, Schwedhelm E, Zeller T
J AM HEART ASSOC. 2016;5(4):e002565.

Oral supplementation with L-homoarginine in young volunteers
Atzler D, Schönhoff M, Cordts K, Ortland I, Hoppe J, Hummel F, Gerloff C, Jaehde U, Jagodzinski A, Böger R, Choe C, Schwedhelm E
BRIT J CLIN PHARMACO. 2016;82(6):1477-1485.

Homoarginine and l-Arginine/Glycine Amidinotransferase in Stroke
Choe C, Schwedhelm E, Atzler D
2016. L-Arginine in Clinical Nutrition. Patel V, Preedy V, Rajendram R (Hrsg.). 1. Aufl. Springer International Publishing, 213-223.

Transcriptomic and metabolic analyses reveal salvage pathways in creatine-deficient AGAT(-/-) mice
Stockebrand M, Nejad A, Neu A, Kharbanda K, Sauter K, Schillemeit S, Isbrandt D, Choe C
AMINO ACIDS. 2016;48(8):2025-39.

L-homoarginine and cardiovascular disease
Atzler D, Schwedhelm E, Choe C
CURR OPIN CLIN NUTR. 2015;18(1):83-8.

Measurement of homoarginine in human and mouse plasma by LC-MS/MS and ELISA: a comparison and a biological application
Cordts K, Atzler D, Qaderi V, Sydow K, Böger R, Choe C, Schwedhelm E
AMINO ACIDS. 2015;47(9):2015-22.

Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans
Kayacelebi A, Langen J, Weigt-Usinger K, Chobanyan-Jürgens K, Mariotti F, Schneider J, Rothmann S, Frölich J, Atzler D, Choe C, Schwedhelm E, Huneau J, Lücke T, Tsikas D
AMINO ACIDS. 2015;47(9):1893-908.

Homoarginine supplementation improves blood glucose in diet-induced obese mice
Stockebrand M, Hornig S, Neu A, Atzler D, Cordts K, Böger R, Isbrandt D, Schwedhelm E, Choe C
AMINO ACIDS. 2015;47(9):1921-9.

Homoarginine and cardiovascular outcome in the population-based Dallas Heart Study
Atzler D, Gore M, Ayers C, Choe C, Böger R, de Lemos J, McGuire D, Schwedhelm E
ARTERIOSCL THROM VAS. 2014;34(11):2501-7.

Homoarginine--an independent marker of mortality in heart failure
Atzler D, Rosenberg M, Anderssohn M, Choe C, Lutz M, Zugck C, Böger R, Frey N, Schwedhelm E
INT J CARDIOL. 2013;168(5):4907-9.

Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Choe C, Atzler D, Wild P, Carter A, Böger R, Ojeda Echevarria F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, De Deyn P, Benndorf R, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant P, Magnus T, Zeller T, Isbrandt D, Schwedhelm E
CIRCULATION. 2013;128(13):1451-61.

A clinical and neurobiological case of IgM NMDA receptor antibody associated encephalitis mimicking bipolar disorder.
Choe C, Karamatskos E, Schattling B, Leypoldt F, Liuzzi G, Gerloff C, Friese M, Mulert C
PSYCHIAT RES. 2013;208(2):194-196.

L-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome.
Choe C, Nabuurs C, Stockebrand M, Neu A, Nunes P, Morellini F, Sauter K, Schillemeit S, Hermans-Borgmeyer I, Marescau B, Heerschap A, Isbrandt D
HUM MOL GENET. 2013;22(1):110-123.

Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake.
Nabuurs C, Choe C, Veltien A, Kan H, van Loon L, Rodenburg R, Matschke J, Wieringa B, Kemp G, Isbrandt D, Heerschap A
J PHYSIOL-LONDON. 2013;591(Pt 2):571-592.

CCM3 Mutations Are Associated with Early-Onset Cerebral Hemorrhage and Multiple Meningiomas
Riant F, Bergametti F, Fournier H, Chapon F, Michalak-Provost S, Cecillon M, Lejeune P, Hosseini H, Choe C, Orth M, Bernreuther C, Boulday G, Denier C, Labauge P, Tournier-Lasserve E
Mol Syndromol. 2013;4(4):165-72.

Acute cerebrovascular disease in the Young: the Stroke in Young Fabry Patients study
Rolfs A, Fazekas F, Grittner U, Dichgans M, Martus P, Holzhausen M, Böttcher T, Heuschmann P, Tatlisumak T, Tanislav C, Jungehulsing G, Giese A, Putaala J, Huber R, Bodechtel U, Lichy C, Enzinger C, Schmidt R, Hennerici M, Kaps M, Kessler C, Lackner K, Paschke E, Meyer W, Mascher H, Riess O, Kolodny E, Norrving B
STROKE. 2013;44(2):340-9.

Differential regulation of AMPK activation in leptin- and creatine-deficient mice
Stockebrand M, Sauter K, Neu A, Isbrandt D, Choe C
FASEB J. 2013;27(10):4147-56.

CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.
Choe C, Lardong K, Gelderblom M, Ludewig P, Leypoldt F, Koch Nolte F, Gerloff C, Magnus T
PLOS ONE. 2011;6(5):19046.

Nitroxyl in the central nervous system.
Choe C, Lewerenz J, Gerloff C, Magnus T, Donzelli S
ANTIOXID REDOX SIGN. 2011;14(9):1699-1711.

Multiple cerebral cavernous malformations and a novel CCM3 germline deletion in a German family.
Choe C, Riant F, Gerloff C, Tournier-Lasserve E, Orth M
J NEUROL. 2010;257(12):2097-2098.

HNO exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Choe C, Lewerenz J, Fischer G, Uliasz T, Espey M, Hummel F, Bruce King S, Schwedhelm E, Böger R, Gerloff C, Hewett S, Magnus T, Donzelli S
J NEUROCHEM. 2009.

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity
Choe C, Lewerenz J, Fischer G, Uliasz T, Espey M, Hummel F, King S, Schwedhelm E, Böger R, Gerloff C, Hewett S, Magnus T, Donzelli S
J NEUROCHEM. 2009;110(6):1766-73.

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.
Gelderblom M, Leypoldt F, Steinbach K, Behrens D, Choe C, Siler D, Arumugam T, Orthey E, Gerloff C, Tolosa E, Magnus T
STROKE. 2009;40(5):1849-1857.

Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.
Leypoldt F, Choe C, Gelderblom M, von Leitner E, Atzler D, Schwedhelm E, Gerloff C, Sydow K, Böger R, Magnus T
PLOS ONE. 2009;4(10):7337.

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.
Geng L, Boehmerle W, Maeda Y, Okuhara D, Tian X, Yu Z, Choe C, Anyatonwu G, Ehrlich B, Somlo S
P NATL ACAD SCI USA. 2008;105(41):15920-15925.

The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork.
Choe C, Ehrlich B
Sci STKE. 2006;2006(363):15.

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
Choe C, Schulze-Bahr E, Neu A, Xu J, Zhu Z, Sauter K, Bähring R, Priori S, Guicheney P, Mönnig G, Neapolitano C, Heidemann J, Clancy C, Pongs O, Isbrandt D
HUM MOL GENET. 2006;15(19):2888-2902.

Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons.
Jacob S, Choe C, Uhlen P, DeGray B, Yeckel M, Ehrlich B
J NEUROSCI. 2005;25(11):2853-2864.

Functional coupling of chromogranin with the inositol 1,4,5-trisphosphate receptor shapes calcium signaling.
Choe C, Harrison K, Grant W, Ehrlich B
J BIOL CHEM. 2004;279(34):35551-35556.

A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.
Thrower E, Choe C, So S, Jeon S, Ehrlich B, Yoo S
J BIOL CHEM. 2003;278(50):49699-49706.

Letzte Aktualisierung aus dem FIS: 18.10.2019 - 00:37 Uhr