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Publikationen

         
2013

1.DHEA(S)--a novel marker in Cushing's disease.

Burkhardt T, Schmidt NO, Vettorazzi E, Aberle J, Mengel M, Flitsch J.

Acta Neurochir (Wien). 2013 Mar;155(3):479-84; discussion 484. doi: 10.1007/s00701-012-1596-6. Epub 2013 Jan 13.

PMID: 23314986 [PubMed - in process]
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2012        

 

Case report: surviving a tiger attack.

Emami P, Kaiser TM, Regelsberger J, Goebell E, Fiehler J, Westphal M, Heese O.
Neurosurg Rev. 2012 Jul 10. [Epub ahead of print]
PMID: 22777659 [PubMed - as supplied by publisher]
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[Fatal crossbow injury in an adolescent].
Hessler C, Hamel W, Kluge S, Mayer U, Grzyska U, Westphal M, Püschel K.
Arch Kriminol. 2012 Mar-Apr;229(3-4):90-5. German.
PMID: 22611907 [PubMed - indexed for MEDLINE]
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NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality.
Stupp R, Wong ET, Kanner AA, Steinberg D, Engelhard H, Heidecke V, Kirson ED, Taillibert S, Liebermann F, Dbalý V, Ram Z, Villano JL, Rainov N, Weinberg U, Schiff D, Kunschner L, Raizer J, Honnorat J, Sloan A, Malkin M, Landolfi JC, Payer F, Mehdorn M, Weil RJ, Pannullo SC, Westphal M, Smrcka M, Chin L, Kostron H, Hofer S, Bruce J, Cosgrove R, Paleologous N, Palti Y, Gutin PH.
Eur J Cancer. 2012 May 18. [Epub ahead of print]
PMID: 22608262 [PubMed - as supplied by publisher]
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Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K.
Breast Cancer Res. 2012 Mar 19;14(2):R49. [Epub ahead of print]
PMID: 22429330 [PubMed - as supplied by publisher]
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Glioblastoma stem-like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration.
Schulte A, Günther HS, Martens T, Zapf S, Riethdorf S, Wülfing C, Stoupiec M, Westphal M, Lamszus K.
Clin Cancer Res. 2012 Apr 1;18(7):1901-13. Epub 2012 Feb 7.
PMID: 22316604 [PubMed - in process]
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Patient satisfaction after anterior cervical discectomy and fusion is primarily driven by relieving pain.
Hessler C, Boysen K, Regelsberger J, Vettorazzi E, Winkler D, Westphal M.
Clin J Pain. 2012 Jun;28(5):398-403.
PMID: 22193847 [PubMed - in process]
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Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
Reifenberger G, Hentschel B, Felsberg J, Schackert G, Simon M, Schnell O, Westphal M, Wick W, Pietsch T, Loeffler M, Weller M; for the German Glioma Network.
Int J Cancer. 2012 Sep 15;131(6):1342-1350. doi: 10.1002/ijc.27385. Epub 2012 Jan 11.
PMID: 22139906 [PubMed - as supplied by publisher]

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CSF fistulas after transsphenoidal pituitary surgery--a solved problem?
Malik MU, Aberle JC, Flitsch J.
J Neurol Surg A Cent Eur Neurosurg. 2012 Sep;73(5):275-80. doi: 10.1055/s-0032-1304808. Epub 2012 Aug 16.
PMID:
22899227
[PubMed - indexed for MEDLINE]
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Salivary cortisol as a diagnostic tool for Cushing's syndrome and adrenal insufficiency: improved screening by an automatic immunoassay.
Deutschbein T, Broecker-Preuss M, Flitsch J, Jaeger A, Althoff R, Walz MK, Mann K, Petersenn S.
Eur J Endocrinol. 2012 Apr;166(4):613-8. doi: 10.1530/EJE-11-0945. Epub 2012 Jan 3.
PMID:
22214924
[PubMed - indexed for MEDLINE]
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DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
Plöckinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, Flitsch J, Vajkoczy P, Jakob W, Saeger W, Schulz S, Dohrmann C.
Eur J Endocrinol. 2012 Feb;166(2):223-34. doi: 10.1530/EJE-11-0737. Epub 2011 Nov 7.
PMID:
22065857
[PubMed - indexed for MEDLINE]
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Metformin after bariatric surgery--an acid problem.
Aberle J, Reining F, Dannheim V, Flitsch J, Klinge A, Mann O.
Exp Clin Endocrinol Diabetes. 2012 Mar;120(3):152-3. doi: 10.1055/s-0031-1285911. Epub 2011 Sep 13.
PMID:
21915819
[PubMed - indexed for MEDLINE]
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2011


1. Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang Z, Aldape KD, Mischel PS, Liau LM, Escovedo CJ, Chen W, Nghiemphu PL, James CD, Prados MD, Westphal M, Lamszus K, Cloughesy T, Phillips HS.
J Clin Oncol. 2011 Dec 1;29(34):4482-90. Epub 2011 Oct 24.
PMID: 22025148 [PubMed - indexed for MEDLINE]
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2. Clinical relevance of associated aneurysms with arteriovenous malformations of the posterior fossa.
Schmidt NO, Reitz M, Raimund F, Treszl A, Grzyska U, Westphal M, Regelsberger J.
Acta Neurochir Suppl. 2011;112:131-5.
PMID: 21692001 [PubMed - indexed for MEDLINE]
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3. How to deal with incompletely treated AVMs: experience of 67 cases and review of the literature.
Reitz M, Schmidt NO, Vukovic Z, Grzyska U, Zeumer H, Westphal M, Regelsberger J.
Acta Neurochir Suppl. 2011;112:123-9. Review.
PMID: 21692000 [PubMed - indexed for MEDLINE]
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4. A survey on clinical study participation and study infrastructure at non-university hospitals in Germany.
Heese O, Böger RH, Westphal M.
Int J Clin Pharmacol Ther. 2011 Sep;49(9):531-5.
PMID: 21888865 [PubMed - indexed for MEDLINE]
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5. The neurobiology of gliomas: from cell biology to the development of therapeutic approaches.
Westphal M, Lamszus K.
Nat Rev Neurosci. 2011 Aug 3;12(9):495-508. doi: 10.1038/nrn3060. Review.
PMID: 21811295 [PubMed - indexed for MEDLINE]
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6. Blister-like aneurysms--a diagnostic and therapeutic challenge.
Regelsberger J, Matschke J, Grzyska U, Ries T, Fiehler J, Köppen J, Westphal M.
Neurosurg Rev. 2011 Oct;34(4):409-16. Epub 2011 May 17. Review.
PMID: 21584689 [PubMed - indexed for MEDLINE]
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7. [Functional and radiological outcome after ACDF in 67 cases].
Hessler C, Boysen K, Westphal M, Regelsberger J.
Z Orthop Unfall. 2011 Dec;149(6):683-7. Epub 2011 Apr 8. German.
PMID: 21480172 [PubMed - indexed for MEDLINE]
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8. Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
Stummer W, van den Bent MJ, Westphal M.
Acta Neurochir (Wien). 2011 Jun;153(6):1211-8. Epub 2011 Apr 9.
PMID: 21479583 [PubMed - indexed for MEDLINE]
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9. Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, Westphal M, Schackert G, Kreth FW, Pietsch T, Löffler M, Weller M, Reifenberger G, Tonn JC; German Glioma Network.
Int J Cancer. 2011 Aug 1;129(3):659-70. doi: 10.1002/ijc.26083.
PMID: 21425258 [PubMed - indexed for MEDLINE]
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10. Consensus document on European brain research.
Di Luca M, Baker M, Corradetti R, Kettenmann H, Mendlewicz J, Olesen J, Ragan I, Westphal M.
Eur J Neurosci. 2011 Mar;33(5):768-818. doi: 10.1111/j.1460-9568.2010.07596.x.
PMID: 21385235 [PubMed - indexed for MEDLINE]
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11. A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.
Schulte A, Günther HS, Phillips HS, Kemming D, Martens T, Kharbanda S, Soriano RH, Modrusan Z, Zapf S, Westphal M, Lamszus K.
Glia. 2011 Apr;59(4):590-602. doi: 10.1002/glia.21127. Epub 2011 Feb 3.
PMID: 21294158 [PubMed - indexed for MEDLINE]
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12. 56-year old woman with sphenoid wing tumor.
Reitz M, Zustin J, Matschke J, Schmidt NO, Westphal M.
Brain Pathol. 2011 Mar;21(2):225-8. doi: 10.1111/j.1750-3639.2010.00471.x. No abstract available.
PMID: 21269338 [PubMed - indexed for MEDLINE]
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13. Beneficial effects of concomitant neuronal and inducible nitric oxide synthase inhibition in ovine burn and inhalation injury.
Lange M, Hamahata A, Enkhbaatar P, Cox RA, Nakano Y, Westphal M, Traber LD, Herndon DN, Traber DL.
Shock. 2011 Jun;35(6):626-31.
PMID: 21263377 [PubMed - indexed for MEDLINE]
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14. Congenital cervical tethered cord in an adult: utility of spinal diffusion tensor MR imaging.
Schmidt NO, Raimund F, Förster AF, Matschke J, Regelsberger J, Fiehler J, Winkler D, Westphal M.
Cent Eur Neurosurg. 2011 Nov;72(4):208-10. doi: http://dx.doi.org/10.1055/s-0030-1268501. Epub 2010 Dec 13. No abstract available.
PMID: 21154217 [PubMed - indexed for MEDLINE]
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15. Signal intensity in T2' magnetic resonance imaging is related to brain glioma grade.
Saitta L, Heese O, Förster AF, Matschke J, Siemonsen S, Castellan L, Westphal M, Fiehler J, Goebell E.
Eur Radiol. 2011 May;21(5):1068-76. Epub 2010 Nov 11.
PMID: 21069342 [PubMed - indexed for MEDLINE]
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16. Training microneurosurgery - four years experiences with an in vivo model.
Regelsberger J, Heese O, Horn P, Kirsch M, Eicker S, Sabel M, Westphal M.
Cent Eur Neurosurg. 2011 Nov;72(4):192-5. doi: http://dx.doi.org/10.1055/s-0030-1261906. Epub 2010 Jul 15.
PMID: 20635313 [PubMed - indexed for MEDLINE]
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17. Non-conventional treatments sought by patients after surgery for intramedullary spinal cord tumors.
Raimund F, Nickel S, Hessler C, Regelsberger J, Westphal M, Heese O.
Cent Eur Neurosurg. 2011 May;72(2):71-4. Epub 2010 May 21.
PMID: 20496309 [PubMed - indexed for MEDLINE]

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Ectopic craniopharyngioma.
Kordes U, Flitsch J, Hagel C, Goebell E, Schwarz R, Herberhold T, von Bueren AO, Rutkowski S, Müller HL.
Klin Padiatr. 2011 May;223(3):176-7. doi: 10.1055/s-0031-1273743. Epub 2011 Apr 1. No abstract available.
PMID:
21462099
[PubMed - indexed for MEDLINE]
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Surgical strategies in childhood craniopharyngioma.
Flitsch J, Müller HL, Burkhardt T.
Front Endocrinol (Lausanne). 2011;2:96. doi: 10.3389/fendo.2011.00096. Epub 2011 Dec 23.
PMID:
22645514
[PubMed]
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2010:
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, James CD, VandenBerg SR, Costello JF, Moorefield S, Cowdrey CJ, Prados M, Phillips HS. Cancer Cell. 2010 Apr 13;17(4):362-75.

A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells.
Hansen K, Müller FJ, Messing M, Zeigler F, Loring JF, Lamszus K, Westphal M, Schmidt NO. Neuro Oncol. 2010 Feb 14.

Structure and in Vitro Biological Testing of Water-Based Ferrofluids Stabilized by Monocarboxylic Acids.
Avdeev MV, Mucha B, Lamszus K, Ve#ka#s L, Garamus VM, Feoktystov AV, Marinica O, Turcu R, Willumeit R. Langmuir. 2010 Feb 4.

Synchrotron-microcomputed tomography studies of normal and pathological cranial sutures: further insight.
Regelsberger J, Schmidt T, Busse B, Herzen J, Tsokos M, Amling M, Beckmann F. J Neurosurg Pediatr. 2010 Mar;5(3):238-42.

Therapeutic clues in spinal dural arteriovenous fistulas - a 30 year experience of 156 cases.
Hessler C, Regelsberger J, Grzyska U, Illies T, Zeumer H, Westphal M. Cen Eur Neurosurg. 2010 Feb;71(1):8-12. Epub 2009 Sep 25.

Inhibition of thromboxane synthase activity improves glioblastoma response to alkylation chemotherapy.
Schmidt NO, Ziu M, Cargioli T, Westphal M, Giese A, Black PM, Carroll RS. Transl Oncol. 2010 Feb;3(1):43-9.

Increase in tumor size following intratumoral injection of immunostimulatory CpG-containing oligonucleotides in a rat glioma model.
Ginzkey C, Eicker SO, Marget M, Krause J, Brecht S, Westphal M, Hugo HH, Mehdorn HM, Steinmann J, Hamel W. Cancer Immunol Immunother. 2010 Apr;59(4):541-51. Epub 2009 Oct 2.

Incorporating BCNU wafers into malignant glioma treatment: European case studies.
Balossier A, Dörner L, Emery E, Heese O, Mehdorn HM, Menei P, Singh J. Clin Drug Investig. 2010;30(3):195-204.

Mit Akromegalie assoziierte Veränderungen der Nasenschleimhaut
Flitsch J, Lüdecke DK, Saeger W, Veit JA, Metternich FU:. HNO 2009

Cushing's disease
Flitsch J, Lüdecke DK, Saeger W: In: : Neuro-Oncology of CNS Tumors . 2nd Edition  JC Tonn, M Westphal, Rutka JT, Grossman SA (eds) Springer Verlag, 231-236, 2010

Functioning Adenomas
Lüdecke DK, Abe T, Flitsch J, Petersenn S, Saeger W In: Neuro-Oncology of CNS Tumors. 2nd Edition Tonn JC, Westphal M, Rutka JT, Grossman SA (eds),
Springer Verlag, Heidelberg-Berlin, 219-238, 2010

 


 

2009:

 

RON receptor tyrosine kinase in human gliomas: expression, function, and identification of a novel soluble splice variant.
Eckerich C, Schulte A, Martens T, Zapf S, Westphal M, Lamszus K. J Neurochem. 2009 May;109(4):969-80. Epub 2009 Mar 6.

Other experimental therapies for glioma.
Westphal M, Lamszus K. Recent Results Cancer Res. 2009;171:155-64. Review.

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, Schramm J, Westphal M, Schackert G, Simon M, Tonn JC, Heese O, Krex D, Nikkhah G, Pietsch T, Wiestler O, Reifenberger G, von Deimling A, Loeffler M. J Clin Oncol. 2009 Dec 1;27(34):5743-50. Epub 2009 Oct 5.

Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche.
Schmidt NO, Koeder D, Messing M, Mueller FJ, Aboody KS, Kim SU, Black PM, Carroll RS, Westphal M, Lamszus K. Brain Res. 2009 May 1;1268:24-37. Epub 2009 Mar 10.

Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK.
Grzelinski M, Steinberg F, Martens T, Czubayko F, Lamszus K, Aigner A. Neoplasia. 2009 Feb;11(2):145-56.

Waking up the brain: a case study of stimulation-induced wakeful unawareness during anaesthesia.
Moll CK, Sharott A, Hamel W, Münchau A, Buhmann C, Hidding U, Zittel S, Westphal M, Müller D, Engel AK. Prog Brain Res. 2009;177:125-45.

Intracranial aneurysms in childhood: report of 8 cases and review of the literature.
Regelsberger J, Heese O, Martens T, Ries T, Kunkel P, Westphal M. Cen Eur Neurosurg. 2009 May;70(2):79-85. Epub 2009 May 25. Review

Successful GPi deep brain stimulation in a patient with adult onset primary axial dystonia.
Zittel S, Moll CK, Hamel W, Buhmann C, Engel AK, Gerloff C, Münchau A. J Neurol Neurosurg Psychiatry. 2009 Jul;80(7):811-2.

Effects of DBS, premotor rTMS, and levodopa on motor function and silent period in advanced Parkinson's disease.
Bäumer T, Hidding U, Hamel W, Buhmann C, Moll CK, Gerloff C, Orth M, Siebner HR, Münchau A. Mov Disord. 2009 Apr 15;24(5):672-6.

Secretory meningiomas: a benign subgroup causing life-threatening complications.
Regelsberger J, Hagel C, Emami P, Ries T, Heese O, Westphal M. Neuro Oncol. 2009 Dec;11(6):819-24. Epub .

Territorial and microvascular perfusion impairment in brain arteriovenous malformations.
Fiehler J, Illies T, Piening M, Säring D, Forkert N, Regelsberger J, Grzyska U, Handels H, Byrne JV. AJNR Am J Neuroradiol. 2009 Feb;30(2):356-61. Epub 2008 Nov 11.

Development of pulmonary hypertension in adults after ventriculoatrial shunt implantation.
Kluge S, Baumann HJ, Regelsberger J, Kehler U, Koziej B, Klose H, Greinert U, Kreymann G, Meyer A. Respiration. 2009;78(1):30-5. Epub 2008 Sep 18.

Dynamics of neurological deficit after surgical decompression of symptomatic vertebral metastases.
Hessler C, Burkhardt T, Raimund F, Regelsberger J, Vettorazzi E, Madert J, Eggers C. Spine (Phila Pa 1976). 2009 Mar 15;34(6):566-71.

Lumbar spinal stenosis: prognostic factors for bilateral microsurgical decompression using a unilateral approach.
Papavero L, Thiel M, Fritzsche E, Kunze C, Westphal M, Kothe R. Neurosurgery. 2009 Dec;65(6 Suppl):182-7; discussion187.

The translaminar approach to lumbar disc herniations impinging the exiting root.
Papavero L, Langer N, Fritzsche E, Emami P, Westphal M, Kothe R. Neurosurgery. 2008 Mar;62(3 Suppl 1):173-7; discussion 177-8.

Acromegaly-associated lesions of the nasal mucosa. Case report]
Flitsch J, Lüdecke DK, Saeger W, Veit JA, Metternich FU. HNO. 2009 Aug;57(8):845-50. German.

 


 

2008:

 

Inhibition of glioblastoma growth in a highly invasive nude mouse model can be achieved by targeting epidermal growth factor receptor but not vascular endothelial growth factor receptor-2.
Martens T, Laabs Y, Günther HS, Kemming D, Zhu Z, Witte L, Hagel C, Westphal M, Lamszus K. Clin Cancer Res. 2008 Sep 1;14(17):5447-58.

Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.
Günther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K. Oncogene. 2008 May 1;27(20):2897-909. Epub 2007 Nov 26.

Regulatory networks define phenotypic classes of human stem cell lines.
Müller FJ, Laurent LC, Kostka D, Ulitsky I, Williams R, Lu C, Park IH, Rao MS, Shamir R, Schwartz PH, Schmidt NO, Loring JF. Nature. 2008 Sep 18;455(7211):401-5. Epub 2008 Aug 24.

Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias.
Stummer W, Reulen HJ, Meinel T, Pichlmeier U, Schumacher W, Tonn JC, Rohde V, Oppel F, Turowski B, Woiciechowsky C, Franz K, Pietsch T; ALA-Glioma Study Group.Neurosurgery. 2008 Mar;62(3):564-76; discussion 564-76

Reduced perception of dyspnea and pain after right insular cortex lesions.
Schön D, Rosenkranz M, Regelsberger J, Dahme B, Büchel C, von Leupoldt A. Am J Respir Crit Care Med. 2008 Dec 1;178(11):1173-9. Epub 2008 Sep 5.

Hypophysectomy for prostate cancer: a revival of old knowledge?
Flitsch J, Bernreuther C, Hagel C, Lüdecke DK: J Neurosurg. 2008 Oct; 109(4):760-4

 

Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes.
Aberle J, Flitsch J, Beck NA, Mann O, Busch P, Peitsmeier P, Beil FU. Mol Genet Metab. 2008 Nov;95(3):188-91. Epub 2008 Sep 23.

A 61-year-old man with hyponatremia.
Bernreuther C, Flitsch J, Lüdecke DK, Hagel C. Brain Pathol. 2008 Apr;18(2):283-7.

[Prognosis after surgical treatment of spinal metastases due to lung cancer]
Hessler C, Regelsberger J, Raimund F, Heese O, Madert J, Eggers C. Chirurg. 2008 Jul;79(7):671-9. German.

Detection of a possible epilepsy focus in a preoperated patient by perfusion SPECT and computer-aided subtraction analysis.
Apostolova I, Lindenau M, Fiehler J, Heese O, Wilke F, Clausen M, Stodieck S, Buchert R.Nuklearmedizin. 2008;47(5):N65-8.

Management of cerebral arteriovenous malformations associated with symptomatic congestive intracranial hypertension.
Rosenkranz M, Regelsberger J, Zeumer H, Grzyska U. Eur Neurol. 2008;59(1-2):62-6. Epub 2007 Oct 4.

Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome.
Moll CK, Hamel W, Ostertag CB, Müller D, Finsterbusch J, Engel AK, Münchau A. Mov Disord. 2008 Sep 15;23(12):1751-6.

 

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Letzte Änderung: Torge Huckhagel, 27.03.2013