Publikationen 2008
Benten D, Staufer K, Sterneck M.
Orthotopic liver transplantation and what to do during follow-up: recommendations for the practitioner.
Nat Clin Pract Gastroenterol Hepatol. 2008 Nov 25.
http://www.ncbi.nlm.nih.gov/sites/entrez/19029996 Benten D, Sterneck M, Panse J, Rogiers X, Lohse AW.
Low recurrence of preexisting extrahepatic malignancies after liver transplantation.
Liver Transpl. 2008 Jun;14(6):789-98.
http://www.ncbi.nlm.nih.gov/sites/entrez/18412260
Berna MJ, Annibale B, Marignani M, Luong TV, Corleto V, Pace A, Ito T,
Liewehr D, Venzon DJ, Delle Fave G, Bordi C, Jensen RT.
A prospective study of gastric carcinoids and enterochromaffin-like cell
changes in Multiple Endocrine Neoplasia Type I and Zollinger-Ellison
syndrome: Identification of risk factors.
J Clin Endocrinol Metab. 2008 Feb 12
http://www.ncbi.nlm.nih.gov/sites/entrez/18270260
Brattig NW, Kowalsky K, Liu X, Burchard GD, Kamena F, Seeberger PH:
Plasmodium falciparum glycosylphosphatidylinositol toxin interacts with the membrane of non-parasitized red blood cells: a putative mechanism contributing to malaria anemia.
Microbes Infect. 10 (2008) 885-91.
http://www.ncbi.nlm.nih.gov/sites/entrez/ 18657459
Burchard GD:
Auch an extrem seltene Diagnosen denken: südamerikanische hämorrhagische Fieber.
Flug-, Tropen- und Reisemedizin 15 (2008) 85-88
Burchard GD:
GeoSentinel - das globale Surveillance-Netzwerk.
Flug-, Tropen- und Reisemedizin 15 (2008) 78-80
C. Frenzel und A.W. Lohse
Leberschäden durch arzneiliche, pflanzliche und nahrungsergänzende Mittel: pathophysiologische Grundlagen
Verdauungskrankheiten 26/3 (2008): S. 88-96
Cramer JP, Burchard GD, Lohse AW.
Old dogmas and new perspectives in antibiotic-associated diarrhea
Med Klin (Munich). 2008 May 15;103(5):325-38; quiz 339-40.
http://www.ncbi.nlm.nih.gov/sites/entrez/18484219
Cramer JP, Lepenies B, Kamena F, Hölscher C, Freudenberg MA, Burchard GD, Wagner H, Krischning CJ, Seeberger PH, Jacobs T:
MyD88/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection.
Microbes and Infection 10 (2008) 1259-65
http://www.ncbi.nlm.nih.gov/sites/entrez/18692153
Dandri M, Murray JM, Lutgehetmann M, Volz T, Lohse AW, Petersen J.
Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.
Hepatology. 2008 Oct;48(4):1079-86.
http://www.ncbi.nlm.nih.gov/sites/entrez/18697217
Denzer UW, Lohse AW.
[Mini laparoscopy]
Dtsch Med Wochenschr. 2008 Jul;133(30):1585-8. German.
http://www.ncbi.nlm.nih.gov/sites/entrez/18642224
Ehrhardt S, Burchard GD:
Eosinophilie bei Tropenrückkehrern und Migranten
Dsch Ärztebl 105 (2008) 801-807
Follenzi A, Benten D, Novikoff P, Faulkner L, Raut S, Gupta S.
Transplanted endothelial cells repopulate the liver endothelium and correct the phenotype of hemophilia A mice. J Clin Invest. 2008 Mar;118(3):93545.
http://www.ncbi.nlm.nih.gov/sites/entrez/18274668
Gontarewicz A, Balabanov S, Keller G, Colombo R, Graziano A, Pesenti E, Benten D, Bokemeyer C, Fiedler W, Moll J, Brümmendorf TH.
Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.
Blood. 2008 Apr 15;111(8):4355-64.
http://www.ncbi.nlm.nih.gov/sites/entrez/18268096
Grabowski P, Schrader J, Wagner J, Hörsch D, Arnold R, Arnold CN,
Georgieva I, Stein H, Zeitz M, Daniel PT, Sturm I.
Loss of nuclear p27 expression and its prognostic role in relation to
cyclin E and p53 mutation in gastroenteropancreatic neuroendocrine tumors.
Clin Cancer Res. 2008 Nov 15;14(22):7378-84.
http://www.ncbi.nlm.nih.gov/sites/entrez/19010853
Günther A, Burchard GD, Schönfeld, C:
Correspondence: Rabies vaccination and traffic accidents.
Travel Med Inf Dis 6 (2008) 326-327
http://www.ncbi.nlm.nih.gov/sites/entrez/18760258
Halangk J, Sarrazin C, Neumann K, Puhl G, Mueller T, Teuber G, Klinker H, Hinrichsen H, Buggisch P, Landt O, Weich V, Bergk A, Wiedenmann B, Neuhaus P, Berg T, Witt H.
Evaluation of complement factor 5 variants as genetic risk factors for the development of advanced fibrosis in chronic hepatitis C infection.
J Hepatol 2008;49:339-45.
http://www.ncbi.nlm.nih.gov/sites/entrez/18644651
Hatz C, Soto J, Nothdurft HD, Zoller T, Weitzel T, Loutan L, Bricaire F, Gay F, Burchard GD, Andriano K, Lefèvre G, de Palacios PI, Genton B:
Treatment of acute uncomplicated falciparum malaria with artemether-lumefantrine in non-immune populations: a safety, efficacy, and pharmacokinetic study.
Am J Trop Med Hyg 78 (2008) 241-247
http://www.ncbi.nlm.nih.gov/sites/entrez/18256423
Hennes EM, Oo YH, Schramm C, Denzer U, Buggisch P, Wiegard C, Kanzler S, Schuchmann M, Boecher W, Galle PR, Adams DH, Lohse AW.
Mycophenolate Mofetil as Second Line Therapy in Autoimmune Hepatitis?
Am J Gastroenterol 2008;103:1-8
http://www.ncbi.nlm.nih.gov/sites/entrez/18853972
Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, Eisenmann de Torres B, Galle PR, McFarlane I, Dienes HP, Lohse AW; International Autoimmune Hepatitis Group.
Simplified criteria for the diagnosis of autoimmune hepatitis.
Hepatology. 2008 Mar 19;48(1):169-176
http://www.ncbi.nlm.nih.gov/sites/entrez/18537184
Herkel J, Lohse AW.
Significance of autoantibodies.
Hepatology. 2008 Mar;47(3):786-8.
http://www.ncbi.nlm.nih.gov/sites/entrez/18302295
Hofer A, Schmiedel S, Lohse AW, Burchard GD.
Severe ileocolitis refractory to standard medical treatment: a diagnostic dilemma.
Internist (Berl). 2008 Jun 29.
http://www.ncbi.nlm.nih.gov/sites/entrez/18587544
Hofer A, Schmiedel S:
Seltene Ursachen häufiger Erkrankungen: Patient mit chronisch kalzifizierender Pankreatitis und Diabetes mellitus Typ2.
Flug-, Tropen- und Reisemedizin 15 (2008) 191
Huber S, Schrader J, Fritz G, Presser K, Schmitt S, Waisman A, Lüth S, Blessing M, Herkel J, Schramm C.
P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg.
PloS ONE 2008;3:e3302
http://www.ncbi.nlm.nih.gov/sites/entrez/18827879
Inada M, Follenzi A, Cheng K, Surana M, Joseph B, Benten D, Bandi S, Qian H, Gupta S.
Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation.
J Cell Sci. 2008 Apr 1;121(Pt 7):100213.
http://www.ncbi.nlm.nih.gov/sites/entrez/18319302
Jensen RT, Berna MJ, Bingham DB, Norton JA.
Inherited pancreatic endocrine tumor syndromes: advances in molecular
pathogenesis, diagnosis, management, and controversies.
Cancer. 2008 Oct 1;113(7 Suppl):1807-43.
http://www.ncbi.nlm.nih.gov/sites/entrez/18798544
Kasprowicz V., Schulze zur Wiesch J., Kuntzen T., Nolan B., Longworth S., Berical A., McMahon C., Reyor L., Elias N., Kwok W., McGovern B., Freeman G., Chung R. Klenerman P., Lewis-Ximenez L., Walker B., Allen T., Kim A., Lauer G.
PD-1 expression levels on CD8+ and CD4+ T cells are associated with viral load during acute Hepatitis C but do not predict infection outcome. J. Virol. March 2008, Vol. 82 (6) 3154-60.
http://www.ncbi.nlm.nih.gov/sites/entrez/18160439
Kobbe R, Klein P, Adjei S, Amemasor S, Thompson WN, Heidemann H, Nielsen MV, Vohwinkel J, Hogan B, Kreuels B, Bührlen M, Loag W, Ansong D, May J.
A randomised trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children.
Malar J. 2008 Dec 19;7(1):261
http://www.ncbi.nlm.nih.gov/sites/entrez/19099594
Kobbe R, Kramme S, Kreuels B, Adjei S, Kreuzberg C, Panning M, Adjei O, Fleischer B, May J.
Q fever in young children, Ghana.
Emerg Infect Dis. 2008 Feb;14(2):344-6.
http://www.ncbi.nlm.nih.gov/sites/entrez/18258140
Kreuels B, Kobbe R, Adjei S, Kreuzberg C, von Reden C, Bäter K, Klug S, Busch W, Adjei O, May J.
Spatial variation of malaria incidence in young children from a geographically homogeneous area with high endemicity.
J Infect Dis. 2008 Jan 1;197(1):85-93
http://www.ncbi.nlm.nih.gov/sites/entrez/18171290
Lutgehetmann M, Volzt T, Quaas A, Zankel M, Fischer C, Dandri M, Petersen J.
Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.
Antivir Ther. 2008;13(1):57-66.
http://www.ncbi.nlm.nih.gov/sites/entrez/18389899
Lüth S, Herkel J, Kanzler S, Frenzel C, Galle PR, Dienes HP, Schramm C, Lohse AW.
Serologic Markers Compared With Liver Biopsy for Monitoring Disease Activity in Autoimmune Hepatitis.
J Clin Gastroenterol 2008;42(8):926-30.
http://www.ncbi.nlm.nih.gov/sites/entrez/18645526
Lüth S, Huber S, Schramm C, Buch T, Zander S, Stadelmann C, Brück W, Wraith DC, Herkel J, Lohse AW.
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs.
J Clin Invest. 2008 Oct 1;118(10):3403-3410.
http://www.ncbi.nlm.nih.gov/sites/entrez/18802476
Lüth S, Kanzler S, Frenzel C, Kasper HU, Dienes HP, Schramm C, Galle PR, Herkel J, Lohse AW.
Characteristics and Long-term Prognosis of the Autoimmune Hepatitis/Primary Sclerosing Cholangitis Overlap Syndrome.
J Clin Gastroenterol. 2008
http://www.ncbi.nlm.nih.gov/sites/entrez/18769363
Lüth S, Lohse AW
Autoimmune Hepatitis in humans.
Comparative Hepatitis (eds. Weber O, Protzer-Knolle U)
Birkhäuser Verlag 2008
Marcellin P, Heathcote J., Buti M, Gane E., de Man R.A., Krastev Z, Germanidis G., Lee S., Flisiak R., Kaita K.,Manns M., Kotzev I, Tchernev K., Buggisch P, Weilert F, Kurdas O.O., Shiffman M.L., Trinh H, Kay M., Sorbel J, Anderson J., Snow-Lampart A., Mondou E, Quinn J, Rousseau F.
Randomized double-blind Comparison of Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for the Treatment Chronic Hepatitis B.
NEJM accepted
May J, Adjei S, Busch W, Gabor JJ, Issifou S, Kobbe R, Kreuels B, Lell B, Schwarz NG, Adjei O, Kremsner PG, Grobusch MP.
Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon.
Malar J. 2008 Oct 1;7:198
http://www.ncbi.nlm.nih.gov/sites/entrez/18828899
Mix H, Weiler-Normann C, Thimme R, Ahlenstiel G, Shin EC, Herkel J, David CS, Lohse AW, Rehermann B.
Identification of CD4 T-Cell Epitopes in Soluble Liver Antigen/Liver Pancreas Autoantigen in Autoimmune Hepatitis.
Gastroenterology. 2008 Jul 31.
http://www.ncbi.nlm.nih.gov/sites/entrez/18773898
Mizukoshi E, Eisenbach C, Edlin BR, Newton KP, Raghuraman S, Weiler-Normann C, Tobler LH, Busch MP, Carrington M, McKeating JA, O'Brien TR, Rehermann B.
Hepatitis C Virus (HCV)-Specific Immune Responses of Long-Term Injection Drug Users Frequently Exposed to HCV.
J Infect Dis. 2008 May 27
http://www.ncbi.nlm.nih.gov/sites/entrez/18505381
Norton JA, Venzon DJ, Berna MJ, Alexander HR, Fraker DL, Libutti SK, Marx SJ,
Gibril F, Jensen RT.
Prospective study of surgery for primary hyperparathyroidism (HPT) in multiple
endocrine neoplasia-type 1 and Zollinger-Ellison syndrome: long-term outcome of a
more virulent form of HPT.
Ann Surg. 2008 Mar;247(3):501-10.
http://www.ncbi.nlm.nih.gov/sites/entrez/18376196
Petersen J, Dandri M, Mier W, Lütgehetmann M, Volz T, von Weizsäcker F, Haberkorn U, Fischer L, Pollok JM, Erbes B, Seitz S, Urban S.
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.
Nat Biotechnol. 2008 Mar;26(3):335-41.
http://www.ncbi.nlm.nih.gov/sites/entrez/18297057
Presser K, Schwinge D, Wegmann M, Huber S, Schmitt S, Quaas A, Maxeiner JH, Finotto S, Lohse AW, Blessing M, Schramm C.
Coexpression of TGF-{beta}1 and IL-10 Enables Regulatory T Cells to Completely Suppress Airway Hyperreactivity.
J Immunol. 2008 Dec 1;181(11):7751-7758
http://www.ncbi.nlm.nih.gov/sites/entrez/19017964
Rodriguez-Torres M, Govindarajan S, Sola R, Clumeck N, Lissen E, Pessoa M, Buggisch P, Main J, Depamphilis J, Dieterich DT.
Hepatic steatosis in HIV/HCV co-infected patients: Correlates, efficacy and outcomes of anti-HCV therapy: A paired liver biopsy study.
J Hepatol 2008;48:756-64
http://www.ncbi.nlm.nih.gov/sites/entrez/18314217
Schmiedel S, Hertlig S, Degen O, van Lunzen J, Polywka S, Seifert D, Schröder AS Püschel K:
Infektionen durch Gewaltdelikte.
Hamburger Ärzteblatt 63 (2008) 35
Schmiedel S:
Management von Patienten mit hochkontagiösen Infektionskrankheiten - Die Ständige Arbeitsgemeinschaft der Kompetenz- und Beratungszentren (StAKoB).
Schmiedel S:
Der tropische Diabetes mellitus - Basis ist eine chronisch fibrokalkulöse tropische Pankreatitis.
Flug-, Tropen- und Reisemedizin 4 (2008) 188-191
Schramm C, Schneider A, Marx A, Lohse AW.
Adalimumab could suppress the activity of non alcoholic steatohepatitis (NASH).
Z Gastroenterol 2008;46:1369-71.
http://www.ncbi.nlm.nih.gov/sites/entrez/19053005
Schramm C, Schuch G, Lohse A.W..
Sorafenib induced liver failure.
Am J Gastroenterol 2008; 103:2162-3
http://www.ncbi.nlm.nih.gov/sites/entrez/18796127
Schramm C. Primär sklerosierende Cholangitis.
In: Gastroenterologie - Das Referenzwerk für Klinik und Praxis. 2008.
Georg Thieme Verlag KG
Schulze Zur Wiesch J, Wichmann D, Hofer A, van Lunzen J, Burchard GD, Schmiedel S.
Primary HIV infection presenting as haemolytic crisis in a patient with previously undiagnosed glucose 6-phosphate dehydrogenase deficiency.
AIDS. 22 (2008) 1886-8.
http://www.ncbi.nlm.nih.gov/sites/entrez/18753869
Siebler J, Wirtz S, Frenzel C, Schuchmann M, Lohse AW, Galle PR, Neurath MF.
Cutting Edge: A Key Pathogenic Role of IL-27 in T Cell- Mediated Hepatitis.
J Immunol. 2008;180:30-3.
http://www.ncbi.nlm.nih.gov/sites/entrez/18096999
Sydow K, Mondon CE, Schrader J, Konishi H, Cooke JP
Dimethylarginine Dimethylaminohydrolase Overexpression Enhances Insulin Sensitivity.
Arterioscler Thromb Vasc Biol. 2008 Jan 31
http://www.ncbi.nlm.nih.gov/sites/entrez/18239148
T. Kuntzen, J. Timm, A. Berical, N. Lennon, A. Berlin, D. Heckerman, J. Carlson, L. Reyor, M. Kleyman, C. McMahon, J. Schulze zur Wiesch, T. Ledlie, M. Koehrsen, C. Kodira, A. Roberts, G. Lauer, H. Rosen, F. Bihl, A. Cerny, U. Spengler, Z. Liu, A. Kim, Y. Xing, A. Schneidewind, M. Madey, J. Fleckenstein, V. Park, J. Galagan, C. Nusbaum, B. Walker, G. Lake-Bakaar, E. Daar, I. Jacobson, E. Gomperts, B.Edlin, S. Donfield, R. Chung, A. Talal, T. Marion, B. Birren, M. Henn, T. Allen
Naturally occurring dominant resistance mutations to HCV protease and polymerase inhibitors in treatment-naïve patients.
Hepatology. 2008 Dec;48(6):1769-78
http://www.ncbi.nlm.nih.gov/sites/entrez/19026009
Thieringer F, Maass T, Czochra P, Klopcic B, Conrad I, Friebe D, Schirmacher P, Lohse AW, Blessing M, Galle PR, Teufel A, Kanzler S.
Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A.
Gene. 2008 Oct 15;423(1):23-8. Epub 2008 Jun 10.
http://www.ncbi.nlm.nih.gov/sites/entrez/18598744
Thieringer F, Maass T, Czochra P, Klopcic B, Conrad I, Friebe D, Schirmacher P, Lohse AW, Blessing M, Galle PR, Teufel A, Kanzler S.
Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A.
Gene. 2008 Jun 10
http://www.ncbi.nlm.nih.gov/sites/entrez/18598744
Thill M, Strunnikova NV, Berna MJ, Gordiyenko N, Schmid K, Cousins SW,
Thompson DJ, Csaky KG.
Late outgrowth endothelial progenitor cells in patients with age-related macular
degeneration.
Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2696-708.
http://www.ncbi.nlm.nih.gov/sites/entrez/18515596
von Kalckreuth V, Lohse AW, Schramm C.
Unmasking autoimmune hepatitis under immunomodulatory treatment of multiple sclerosis--not only beta interferon.
Am J Gastroenterol. 2008 Aug;103(8):2147-8; author reply 2148.
http://www.ncbi.nlm.nih.gov/sites/entrez/18796115
von Wagner M, Hofmann WP, Teuber G, Berg T, Goeser T, Spengler U, Hinrichsen H, Weidenbach H, Gerken G, Manns M, Buggisch P, Herrmann E, Zeuzem S.
Placebo-controlled trial of 400 mg amantadine combined with peginterferon alfa-2a and ribavirin for 48 weeks in chronic hepatitis C virus-1 infection. Hepatology 2008
http://www.ncbi.nlm.nih.gov/sites/entrez/18846541
Weinke T, Liebold I, Burchard GD, Frühwein N, Grobusch MP, Hatz C, Kollaritsch H, Nothdurft HD, Reisinger E, Rieke B, Schönfeld Ch, Steffen R, Stich A:
Prophylactic immunisation against traveller's diarrhoea caused by enterotoxin-forming strains of Escherichia coli and against cholera: does it make sense and for whom?
Travel Med Infect Dis 6 (2008) 362-7
http://www.ncbi.nlm.nih.gov/sites/entrez/18984481
Wennicke K, Debierre-Grockiego F, Wichmann D, Brattig NW, Pankuweit S, Maisch B, Schwarz RT, Ruppert V.
Glycosylphosphatidylinositol-induced cardiac myocyte death might contribute to the fatal outcome of Plasmodium falciparum malaria.
Apoptosis. 2008 Jul;13(7):857-66.
http://www.ncbi.nlm.nih.gov/sites/entrez/18470700
Wichmann D, Denzer U, Schmiedel S, Lohse AW, Burchard GD:
Differenzialdiagnose des Aszites - keine trockene Routine.
Hamburger Ärzteblatt 62 (2008) 24-25
Wichmann D, Scherpe S, Heese O, Schmiedel S, Burchard GD, Ruckdeschel K, Sobottka I.
If the rumor is tumor, the issue is tissue.
Neurosurgery, 63 (2008):E820
http://www.ncbi.nlm.nih.gov/sites/entrez/18981853
Worns MA, Teufel A, Kanzler S, Shrestha A, Victor A, Otto G, Lohse AW,
Incidence of HAV and HBV Infections and Vaccination Rates in Patients With Autoimmune Liver Diseases.
Am J Gastroenterol 2007
http://www.ncbi.nlm.nih.gov/sites/entrez/17970833
Wunderlich N, Burchard GD:
Tropenerkrankungen des Herzens - Chagas-Krankheit und Echinokokkose.
Der Kardiologe 3 (2008) 239-50
