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Barbara Finckh, PhD, biologist in the Newborn Screening and Metabolic Laboratory of the Institute of Clinical Chemistry/Department of Pediatrics at the University Hospital Hamburg-Eppendorf
Member of Deutsche Gesellschaft für Biochemie und Molekularbiologie (GBM), Society for Free Radical Research, Society for Free Radical Biology and Medicine
Research Topics
Biochemistry of free radicals and their importance in pathopyhsiology of human diseases
Research Interests
Free radical injury may be a pathogenic mechanism in different paediatric diseases. The determination of the oxidant-antioxidant (im)balance requires the measurement of different groups of parameters like the levels of antioxidant defence, antioxidant consumption and radical-induced damage.
Selection of Projects
Selection of Publications
Finckh B (2008) Determination of the oxidant-antioxidant balance in neonatal dried blood spots and blood microsamples. Prog Biochem Biophys 517:206
Finckh B, Foeldvari I, Kohlschütter A (2006) Oxidative stress and inflammatory disease activity in patients with juvenile idiopathic arthritis. Free Radic Biol Med 41 (Suppl 1) S87
Christen S/Finckh B, Lykkesfeldt J, Gessler P, Schaper M, Nielsen P, Schmid ER, Schmitt B (2005) Oxidative stress precedes systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation. Free Radic Biol Med 38:1323-1332
Stuerenburg HJ, Stangneth B, Kohlschütter A, Finckh B (2003) Influence of diagnostic categories, age and gender on antioxidative defense and lipid peroxidation in skeletal muscle of patients with neuromuscular diseases. J Amer Aging Assoc 26:39-46
Finckh B, Kontush A, Commentz J, Hübner C, Burdelski M, Kohlschütter A (1999) HPLC analysis of ubiquinol-10, ubiquinone-10, carotenoids, and tocopherols in neonatal plasma - coulometric electrochemical detection. Methods Enzymol 299:341-348
Funding
Sanitätsrat Dr. Emil Alexander Huebner und Gemahlin-Stiftung
Rickertsen-Stiftung
