ZMNH
Zentrum für Molekulare Neurobiologie
Universitätsklinikum Eppendorf
Martinistr. 52
20246 Hamburg
Tel: +49-40-7410-56275
Fax: +49-40-7410-57700
Email: matthias.kneussel@zmnh.uni-hamburg.de
 

January 23, 1966
 

1987-1993

1993

 
1994-1997

1997

1997-1999

 
1999-2002

 
2001

since Aug/2002

 
2004

 
2005

 
2006

Studies of Biology, Technical University of Darmstadt

Diploma-Project, Max-Planck-Institute for Biophysics, Dept. of Membrane Physiology Frankfurt/Main

PhD Student, University College London, Dept. of Pharmacology, London

Dr. rer. nat., Technical University of Darmstadt

Post-Doctoral Fellow, Max-Planck-Institute for Brain Research, Dept. of Neurochemistry, Frankfurt/Main

Group leader of Neurotransmitter Receptor Group, Dept. of
Neurochemistry, Max-Planck-Institute for Brain Research, Frankfurt/Main

Young Investigator Award of the German Neuroscience Society, NWG

Independent Research Group Leader, ZMNH, Center for Molecular Neurobiology, University of Hamburg Medical School

Habilitation in Biochemistry, University of Frankfurt/Main, Faculty of Biochemistry, Chemistry and Pharmacy

Habilitation in Molecular Biology and Genetics, University of Hamburg, Faculty of Biology

Award of the Chica and Heinz Schaller-Foundation, University of Heidelberg
 

Since 2000 7 PhD-students and 5 Master students
 

Editorial board member, Frontiers in Molecular Neuroscience

Society for Neuroscience, USA

German Neuroscience Society (NWG)

German society for Biochemistry and Molecular Biology (GBM)
 

Neurotransmitter receptor clustering in relationship to synaptic plasticity

Postsynaptic scaffold proteins in relationship to synaptic plasticity

Live cell imaging and intracellular transport of synaptic proteins
 

• Kneussel M, Betz H (2000) Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: the membrane activation model Trends in Neurosciences 23: 429-435

• Kneussel M, Brandstatter JH, Laube B, Stahl S, Muller U, Betz, H (1999) Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice Journal of Neuroscience 19: 9289-9297

• Kneussel M, Haverkamp S, Fuhrmann JC, Wang H, Wassle H, Olsen RW, Betz H (2000) The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A, 97: 8594-8599

• Bavro VN, Sola M, Bracher A, Kneussel M, Betz H, Weissenhorn W (2002) Crystal structure of the GABA(A)-receptor-associated protein GABARAP EMBO Reports, 3: 183-189

• Fuhrmann JC, Kins S, Rostaing P, El Far O, Kirsch J, Sheng M, Triller A, Betz H, Kneussel M (2002) Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes Journal of Neuroscience 22: 5393-5402

• Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe-Siefke C, Kneussel M (2006) Neuronal cotransport of glycine receptor and the scaffold protein gephyrin Journal of Cell Biology 172: 441-451

• Loebrich S, Bähring R, Katsuno T, Tsukita S, Kneussel M (2006) Activated radixin is essential for GABA_A receptor a5 subunit anchoring at the actin cytoskeleton. EMBO Journal 25: 987-999

• Boyl PP, Di Nardo A, Mele A, Mulle C, Sassoe-Pognetto M, Panzanelli P, Kneussel M, Costantini V, Perlas E, Witke W (2007) Increased neuronal excitability and novelty seeking behaviour in mice lacking the actin-binding protein profilin 2 EMBO Journal 26: 2991-3002

• Tagnaouti N, Loebrich S, Pechmann Y, Heisler FF, Fehr S, De Arcangelis A, Georges-Labouesse E, Adams JC, Kneussel M (2007) Neuronal expression of muskelin in the rodent central nervous system. BMC Neuroscience 8: 28.

• Maas, C., Belgardt, D., Lee, H.K., Heisler, F.F., Lappe-Siefke, C., Magiera, M. M., van Dijk, J., Hausrat , T., Janke, C, Kneussel, M. (2009).Synaptic activation modifies microtubules underlying transport of postsynaptic cargo, Proc. Natl. Acad. Sci. USA, in press