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Pharmacology, neurobiology, electrophysiology, biochemistry, cell biology, genetics


Thomas Eschenhagen, Pharmacology
Heimo Ehmke, Physiology
Olaf Pongs, ZMNH Neuronal Signal Transduction

Principal investigators

Project 1:

Role of AE3 and NHE1 for cardiomyocyte homeostasis and remodeling

Christian Hübner and Andreas Gal, Human Genetics

Project 2:

Investigation of IKs and IKr modulation by adrenergic signaling pathways in transgenic mouse models


Olaf Pongs, ZMNH, Institute of Neuronal Signal Transduction


Project 3:

Analysis of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function in adult heart using conditional transgenic mouse models

Dirk Isbrandt and Heimo Ehmke, ZMNH/Physiology

Project 4:

Role of the nucleotides cyclic ADP-ribose, ADP-ribose and NAADP in local and global Ca2+ signaling in mouse cardiac myocytes

Andreas Guse, Biochemistry

Project 5:

Effects and regulation of inhibitor-1 in the heart and its therapeutic potential in heart failure


Ali El-Armouche and Thomas Eschenhagen, Pharmacology


Project 6:

Involvement of the ubiquitin-proteasome system in the pathogenesis of familial hypertrophic cardiomyopathy

Lucie Carrier and Thomas Eschenhagen, Pharmacology

Start: 01. September 2005

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© Universitätsklinikum Hamburg-Eppendorf, Impressum
Letzte Änderung: Frank Neumann, 08.01.2007