Project 1:

Role of AE3 and NHE1 for cardiomyocyte homeostasis and remodeling

Project 2:

Investigation of IKs and IKr modulation by adrenergic signaling pathways in transgenic mouse models

Olaf Pongs, ZMNH, Institute of Neuronal Signal Transduction

Project 3:

Analysis of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function in adult heart using conditional transgenic mouse models

Project 4:

Role of the nucleotides cyclic ADP-ribose, ADP-ribose and NAADP in local and global Ca2+ signaling in mouse cardiac myocytes

Project 5:

Effects and regulation of inhibitor-1 in the heart and its therapeutic potential in heart failure

Ali El-Armouche and Thomas Eschenhagen, Pharmacology

Project 6:

Involvement of the ubiquitin-proteasome system in the pathogenesis of familial hypertrophic cardiomyopathy